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Vaginal Gel to Inhibit HIV

Various tests conducted by scientists to make a vaginal cream that is able to fend off the HIV virus, ended in failure. Now experts who tested the drug was originally used to treat HIV as a prevention drug, by the way embedded in vaginal gels and vaginal contraceptive ring shape.


Way similar to the method of drug to freshen breath or allergy medications, but these are applied in the vagina. The drug was later given the name of microbicides will be more marketable in developing countries because it is usually the men are lazy to use a condom.

For two decades, scientists have struggled to create drugs to prevent HIV is quite strong. Preliminary studies have been tested on women in South Asia in the form of vaginal gel containing the AIDS drug tenofovir, but the new results will be known next July.

Antiretroviral drugs (ARVs) is a revolution in AIDS treatment so that a person with HIV can live longer. These drugs also reduce the risk of virus transmission from pregnant mothers to their babies. Therefore, experts assess if these drugs are consumed every day can give a deterrent effect, both men and women.

Dozens of research have also been conducted on vulnerable populations who are infected. Usually the drugs used dalah tenofovir because it has lower side effects than other antiretroviral drugs.

The problem, taking medication every day can result in resistance (drug resistance), especially if someone forgot to take her medicine. This has sparked controversy.

Research on HIV prevention gel actually started in 1994. At first, scientists know that the cells on the surface of the vagina is not the initial target HIV because the virus rapidly entered the cell layers.

Studies in monkeys showed a small population of cells "compiler" that produces signs several days before the virus ready to spread. Drugs like tenofovir to prevent HIV multiplies despite infecting the body.

According to Dr Salim Abdool Karim of the Centre for AIDS Programme of Research in South Africa, the concentration of tenofovir in the vaginal tissue will be higher when administered in a gel rather than pills.

Learning from the success of contraception, are now the experts to develop tenofovir in other methods, which are easily dissolved into the lining of the vagina so that it will not look mate. In addition it also made tenofovir vaginal rings are coated so that it can survive for long. Available also for gay men, in the form of tenofovir for the rectum.
 
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